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Testing & Services

In-vitro Testing

American Preclinical Services has a broad range of in-vitro testing services. We offer multiple methodologies that can be used for the evaluation of biocompatibility, toxicology and lot-release testing. Depending on your regulatory requirements, our in-vitro services offer tests that meet ISO 10993, USP  <87>, and JMHLW guidelines.

We are passionate about offering alternative methods that can be used for the evaluation of your product. If you have a specific test methodology that may not be in our current scope, please contact us today to discuss availability and/or a validation plan to meet all of your testing needs.

Cytotoxicity Testing

  • Agar Overlay
  • Direct Contact
  • MEM Elution
  • Neutral Red Uptake
  • MTT
  • Limulus Amebocyte Lysate (LAL)

Hemocompatibility Testing

  • Hemolysis (ASTM, USP and JMHLW)
  • Complement Activation C3a and SC5b Assay
  • Partial Thromboplastin Time (PTT)
  • Prothrombin Time Assay (PT)
  • Platelet and Leukocyte
  • In-vitro Blood Loop

Genotoxicity Testing

  • AMES (Bacterial Mutagenicity)
  • Chromosome Aberration
  • Mouse Lymphoma Assay
  • Mouse Micronucleus Assay (Peripheral Blood Method)
 
 
 

Take a look inside at the capabilities that APS has to offer...

American Preclinical Services (APS) is a State of the Art, ISO 17025 accredited, AAALAC accredited, USDA registered and GLP compliant Contract Research Organization (CRO) located in Minneapolis, MN.

We are a comprehensive CRO whose catalogue includes ISO10993, USP, USP, JMHLW, custom biocompatibility testing, interventional, surgical, toxicology, pharmacology, pain, cadaver and bioskills, model development and complete pathology services.

Whether your company is a startup or an established industry leader, APS’ experienced staff is uniquely qualified to tackle your project and meet your in-vivo and in-vitro preclinical research needs in a timely fashion. more