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Testing & Services

Pain Research

APS offers a comprehensive portfolio of rodent pain models designed for the assessment of novel analgesic therapies. We have compiled a highly skilled team of experts in the field of behavioral pharmacology, with experience in the pharmaceutical, medical device, and CRO industries.

As we strive to be your partner in your discovery research efforts, we have built our offerings to encompass models and assays that cover a range of discovery needs. Whether you need to screen a large number of compounds quickly or need to fully characterize a single compound, APS has the capabilities and experience to help you meet your goals.

As experienced pain researchers, we recognize that pain can manifest itself in multiple and diverse ways: hypersensitivity, use-related pain behaviors, and pain-suppressed behaviors to name a few. As such, we have established multiple ways to assess pain-related behaviors and we are constantly striving to add to and refine our offerings.  

Our services include the following endpoints:

Mechanical Allodynia

Mechanical Hyperalgesia

Thermal Hyperalgesia

Weight Bearing

Grip Strenth

Joint Compresion

Spontaneous Flinching

Visceromotor Response (EMG)

Acute Nociception

Intestinal Transit

Take a look inside at the capabilities that APS has to offer...

American Preclinical Services (APS) is a State of the Art, ISO 17025 accredited, AAALAC accredited, USDA registered and GLP compliant Contract Research Organization (CRO) located in Minneapolis, MN.

We are a comprehensive CRO whose catalogue includes ISO10993, USP, USP, JMHLW, custom biocompatibility testing, interventional, surgical, toxicology, pharmacology, pain, cadaver and bioskills, model development and complete pathology services.

Whether your company is a startup or an established industry leader, APS’ experienced staff is uniquely qualified to tackle your project and meet your in-vivo and in-vitro preclinical research needs in a timely fashion. more