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Monthly Archives: October 2018

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Improved Method for the ASTM Platelet and Leukocyte Assay: Use of Minimal Heparinization in a Screening Test for Hemocompatibility of Blood-Contacting Medical Devices

Category : Biocompatibility, In-vitro testing

Abstract Most blood-contacting medical devices must be assessed for potential thrombogenicity prior to regulatory approval. A common assay for screening and qualifying devices involves monitoring the reduction of platelet and leukocyte counts in whole blood exposed to the device. We have validated an improved method for assessing a device’s effect on platelet activation and surface adhesion, offering significant improvement over

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