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APS COVID-19 Response

Working with APS during these Unprecedented Times Updated 7/09/20 As we are all well aware, the spread of Coronavirus (COVID-19) has prompted all of us as individuals and corporations to rethink our current practices to ensure the health and wellness of our communities.  We are constantly adjusting to this ever-evolving situation and are redefining a new […]

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American Preclinical Services Receives AAALAC’s Global 3Rs Award for North America.

American Preclinical Services (APS) has been awarded AAALAC’s Global 3Rs Award for all of North America (there are two-three other winners for other continents). This AAALAC award recognizes our development of a new testing methodology, the In-vitro Blood Loop Assay, as a replacement for the Canine NonAnticoagulated Venous Implant (NAVI) Model for testing thrombogenicity of […]

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Pathology Matters, part 3 of a 3 part series: Semiquantitative Histopathology Scoring

Preclinical studies generating semiquantitative histopathology data are welcomed by regulatory agencies because, theoretically, reproducible and comparable results would be obtained with independent observers. But is that necessarily the case? Many factors influence the interpretation and reproducibility of semiquantitative data. Histopathology results are dependent on establishing appropriate scoring criteria. Semiquantitative scoring, with categorical ranking of observed […]

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Get The Most Out of Your Pathologist

The pathologist’s primary role in a preclinical study is interpreting gross and microscopic tissue changes. But did you know that the pathologist can also be a valuable resource for study planning? Consultation with an experienced pathologist early in the study, ideally during protocol development, contributes to getting the most data for your research dollar. Benefits […]

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