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Tag Archives: Histopathology

Share on Google+ July 10, 2017

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Pathology Matters, part 2 of a 3 part series: Assessing Histopathology Results

Category : Histopathology, Interventional Medicine, Medical Device testing

Part 1 of this series described the preclinical study types relying heavily on histopathology data: device safety, biocompatibility, and systemic toxicity. Here we focus on strategies for histopathology data assessment. Preclinical study histopathology data can generally be divided into three types: Qualitative Quantitative Semiquantitative Qualitative histopathology uses description to document tissue changes and is more applicable to studies where the

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Share on Google+ June 12, 2017

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Pathology Matters, part 1 of a 3 part series: Preclinical Studies and Histopathology

Category : Histopathology, Interventional Medicine, ISO, Medical Device testing

The histopathology evaluation in preclinical studies is performed to support the study objectives. The study type, tissues examined, and intended data use all determine what pathology analysis is needed. Here we review the preclinical studies that rely heavily on histopathology data. Histopathology is a key component of these preclinical study types: Device safety studies Biocompatibility studies Systemic toxicity studies These

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Share on Google+ May 22, 2017

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Dystrophic Mineralization of Costal Cartilage in Hartley Guinea Pigs

Category : Histopathology, Publication, Toixcology

The University of Minnesota College of Veterinary Medicine and American Preclinical Services collaborate to document a previously undocumented novel lesion of Hartley guinea pigs, dystrophic mineralization of costal cartilage, as an incidental finding.  Abstract Hartley guinea pigs are widely used animal models of disease, particularly in studies of osteoarthritis. The purpose of this study was to investigate lesions in the

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Share on Google+ January 23, 2017

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The APS Preclinical Program: Your Path to Success in 2017

Category : Our Laboratories

Finding a reliable partner in the preclinical CRO space can be challenging. In the early stages of product development, having a partner you can trust and rely on is of paramount importance. Welcome to American Preclinical Services. APS is an AAALAC and ISO17025 accredited, USDA registered and GLP compliant preclinical center of excellence located in Minneapolis, MN. At APS, we

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Share on Google+ April 4, 2016

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Get The Most Out of Your Pathologist

Category : Uncategorized

The pathologist’s primary role in a preclinical study is interpreting gross and microscopic tissue changes. But did you know that the pathologist can also be a valuable resource for study planning? Consultation with an experienced pathologist early in the study, ideally during protocol development, contributes to getting the most data for your research dollar. Benefits to all parties include: Selection

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