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Tag Archives: WHHL-MI

Share on Google+ February 23, 2015

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Out of Control Cholesterol – The Watanabe Rabbit as an Animal Model of Familial Hypercholesterolemia

Category : APS Service Offerings, Watanabe Rabbits

What is the Watanabe Rabbit:  The Watanabe Heritable Hyperlipidemic (WHHL-MI) rabbit is an animal model of familial hypercholesterolemia, which is caused by a genetic and functional deficiency in low-density lipoprotein receptors.  This leads to a significant increase in serum cholesterol as compared to normal animals and in this sub-strain, a propensity to develop myocardial infarction.     This sample of

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