Animal Models

APS works with all large and small research animal species with the exception of non-human primates. Our wealth of experiences and capabilities allows us to answer clients research questions and aid with study design. We regularly perform complex animal surgeries and model creations for establishing physiological or mechanical models of disease states. We are also experienced in sample collections and analysis of endpoints for biomarkers of disease.

Non-Genetic (Created) Disease Models

Cardiovascular Models

Aneurysms
Myocardial Infarction
Ischemia Reperfusion
Hypertension
Chronic Total Occlusion (CTO) Arterial Lesions
Chronic Partial Occlusion (CPO) Arterial Lesions
In-stent Restenosis (ISR)
Cardiac Septal Defects
Venous Thrombosis (DVT)
Arteriovenous Fistula
Embolic protection
Endothelialization
Drug deposition

Dermal

Skin Flap Ischemia / Reperfusion
Partial Thickness Wounds
Full Thickness Wounds

Neurovascular Models

Stroke
Aneurysms

Orthopedic

Osteoarthritis
Bone Fracture

Pulmonary

Emphysema
Long Volume Reduction
Pulmonary Function Testing

Tumor Models

Brain Tumor (TVT)
Prostate Tumor (TVT)

Urogenital

Benign Prostate Hyperplasia (BHP)

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