Testing & Services

Testing & Services

We thrive on challenge

See what makes us different

Interventional Capabilities

American Preclinical Services (APS) continues to be a preclincial center of excellence for medical device interventional research.

APS offers the most cutting edge equipment and interventional techniques specifically designed for cardiovascular and peripheral vascular research. APS has three digital cardiac catheterization labs featuring the Siemens AXIOM Artis and Zee fixed C-arm platforms. By having three interchangeble cath labs, all offering the highest quality digital imaging possible, APS can accomodate your timelines no matter how large the study design or last minute the request. Futhermore, our in-house technical experts are among the most experienced interventionalists in preclinical research.

We feature dedicated Siemens Leonardo workstations in each cath lab for real-time quantitative coronary/vascular angiography (QCA/QVA) analysis and evaluation. APS also operates its own dedicated picture archiving and communication system (PACS) server for storing and retrieving cases.

Quantitative angiography may be augmented by additional types of intravascular imaging, including optical coherence tomography (OCT), intravascular ultrasound (IVUS), and intracardiac ultrasound (ICE). 


Imaging and Data Collection Modalities

  • Fluoroscopy (Siemens AXIOM Artis and Zee™ Digital Cath Labs (n=3), Siemens Avantic™ Mobile C-arm)
  • 3D Rotational Fluoroscopy
  • Intravascular Ultrasound (IVUS) (Boston Scientific iLAB™)
  • Optical Coherence Tomography (OCT) (St. Jude Medical C7-XR™)
  • Intracardic (ICE) and Duplex Ultrasound (Siemens Cypress and Sequoia™)
  • EP Mapping (St. Jude Medical NAVx™)
  • EP Recording (Bard LabSystem™ PRO
  • Dual Source Computed Tompgraphy (CT) (Siemens Somatom® Definition)
  • MRI Through Partnerships (Siemens Avanto™ 1.5T, GE Signa HDx 3.0T™)
  • MicroCT Through Partnerships (North Star Imaging)
  • Faxitron (Digital MX20™ and Analog Flat Film) 

APS is experienced in following interventional models and device product testing:


  • Renal Denervation
  • Coronary Vascular Drug Eluting Stents and Scaffolds (DES)
  • Coronary Vascular Bare Metal Stents (BMS)
  • Peripheral Vascular Drug Eluting Stents and Scaffolds (DES)
  • Peripheral Vascular Bare Metal Stents (BMS)
  • Drug Coated Balloons (DCB / DEB)
  • Transcatheter Valve Replacement (TAVI, TAVR)
  • POBA Balloons
  • Aortic Annuloplasty Balloons
  • Guide Wires
  • Guide Catheters
  • Trans-septal Catheters
  • Introducer Sheaths
  • Septal Defect Closure (ASD, PFO, PMVSD)
  • Atherectomy
  • Thrombectomy
  • Embolic Protection
  • Vascular Closure
  • Abdominal Aortic Aneurysm (AAA)
  • Left Atrial Appendage Occlusion
  • Endovascular Grafts
  • Patent ductus Arteriosus Closure
  • Perivalvular Leak Occlusion
  • Embolic Beads
  • Chronic Total Occlusion / Total Partial Occlusion Crossing Wires
  • Telemetry
  • Cell and Gene Therapy
  • Myocardial Infarction Models
  • Vascular Stimulation


  • Cardiac Ablation
  • Cardiac Rhythm Management
  • Cardiac Leads
  • Pulmonary Vein Ablation
  • EP Recording and Mapping


  • Obesity Devices
  • Biliary Catheter


  • Epidural leads
  • Carotid Sinus Stimulation


  • Lung denervation
  • Lung Volume Reduction
  • Lung Biopsy
  • Drug Eluting Stents and Scaffolds (DES)
  • Bare Metal Stents and Scaffolds
  • Tracheal Stent


  • Kidney Cellular Regeneration
  • Prostate Ablation
  • Uterine Ablation

Take a look inside at the capabilities that APS has to offer...

American Preclinical Services (APS) is a State of the Art, ISO 17025 accredited, AAALAC accredited, USDA registered and GLP compliant Contract Research Organization (CRO) located in Minneapolis, MN.

We are a comprehensive CRO whose catalogue includes ISO10993, USP, USP, JMHLW, custom biocompatibility testing, interventional, surgical, toxicology, pharmacology, pain, cadaver and bioskills, model development and complete pathology services.

Whether your company is a startup or an established industry leader, APS’ experienced staff is uniquely qualified to tackle your project and meet your in-vivo and in-vitro preclinical research needs in a timely fashion. more